From Webs to Wires: Unraveling How Humidity Transforms the Electrical Properties of Tarantula and Ghost Spider Silk

Isis Megan Hsu

pp.1-14 DOI: 10.62051/xvw17b43

Abstract: Spider silk has long been an evolution spectacle, possessing the tensile of steel and the elasticity of rubber. There are recent studies that show how humidity elicits different electrical resistance from spider silks. In this study, I investigated these different electrical responses from multiple species, the orb-weaver and tarantula spider. By employing self-designed acrylic test chambers and parallel resistance-measurement setups, I measured changes in electrical resistance from 10^14 Ω … Read More

A Review of ABA in the Regulation of Plant Growth-Drought Resistance Balance

Junce Zhang

pp.15-20 DOI: 10.62051/6c0wmd19

Abstract: Abscisic Acid (ABA) is a core phytohormone for plants to respond to drought stress and balance growth and stress resistance. This paper reviews the upstream perception and initiation of the ABA signaling pathway, the SnRK1-TOR energy hub, transcriptional regulation and downstream responses, as well as the crosstalk mechanism between ABA and other phytohormones including auxin and brassinosteroid (BR). It focuses on the regulatory logic of key nodes in each module, and reveals the dynamic … Read More

From Group Intervention to Precision Strike: Insights from Ebola Virus for Future Infectious Disease Management

Rongwei Yuan

pp.21-28 DOI: 10.62051/w2yw7a07

Abstract: The 2014–2016 West African Ebola outbreak exposed systemic deficiencies in traditional public health approaches to managing highly lethal infectious diseases, while also marking a transformative turning point for breakthroughs in precision medicine technologies. This study systematically examines the Ebola virus, analyzing its transmission scale and historical challenges in containment. By comparing the effectiveness of traditional medical interventions with rapid diagnostics and targeted … Read More

Microplastic Particles and Neural Diseases: Mechanistic Links Between Environmental Exposure and Nervous System Dysfunction

Jiabao Zhu

pp.29-35 DOI: 10.62051/nykq8y06

Abstract: Microplastic particles are widespread environmental contaminants with increasing concern for human neural health. Although direct causal links between microplastic exposure and specific neural diseases remain unproven, experimental evidence suggests that microplastics and nanoplastics may affect the nervous system through multiple interconnected pathways. After ingestion or inhalation, particles may interact with epithelial barriers, immune cells, vascular systems, and the gut microbiota, … Read More

Development Trend of Genetic Improvement of High Protein Maize

Ziheng Xu

pp.36-41 DOI: 10.62051/tcrmp638

Abstract: Global maize production has maintained significant growth in recent years, with total output reaching approximately 1.2 billion tons by 2024. As China's primary food and feed crop, maize holds a core strategic position in the national food security framework. High-protein maize plays a pivotal role in enhancing crop nutritional capacity and global food supply security. Given China's heavy reliance on international markets for protein raw materials, developing and promoting high-protein maize … Read More

Comparative Impact of Bacterial and Yeast Probiotic Strains in Functional Foods: Mechanisms, Efficacy and Applications

Xiaoning Zhang

pp.42-51 DOI: 10.62051/xep28116

Abstract: This review systematically examines four principal probiotic groups in the context of functional food applications: Lactobacillus, represented by L. rhamnosus GG (LGG), which enhances epithelial barrier integrity via SpaCBA pili-mediated adhesion and secreted proteins Msp1/p75 and Msp2/p40 that activate EGFR-Akt signaling to attenuate cytokine-induced apoptosis; Bifidobacterium, which mediates ecosystem-level colonic regulation through acetate-driven cross-feeding with butyrate-producing taxa … Read More

Research on the structural characteristics, mutation evolution and prevention and control strategies of SARS-CoV-2

Siya Gao, Zichen Ma, Guoguo Yang

pp.52-57 DOI: 10.62051/vfg84e05

Abstract: OVID-19, or novel coronavirus pneumonia, is a global infectious disease caused by SARS-CoV-2, which has had a profound impact on public health, socioeconomics, and people's daily lives since its outbreak in 2019. This article reviews the structural composition, mutation evolution, transmission characteristics, and prevention and control measures of SARS-CoV-2. Studies have shown that the virus is mainly composed of spike protein, nucleocapsid protein, and viral RNA. The spike protein mediates … Read More

The Targeted Regulation of Extracellular Vesicles by Natural Active Ingredients for Skin Repair

Shiqi Xu

pp.58-64 DOI: 10.62051/wmjhhb48

Abstract: Extracellular vesicles (EVs), as natural nano EVs, not only have high biocompatibility and strong penetration, but also can achieve targeted delivery, making them an ideal natural drug carrier. Natural active substances have advantages such as multi-target, anti-inflammatory and antioxidant properties, and have good application prospects in the field of skin repair. In recent years, studies have shown that the combination of EVs and natural active ingredients can form significant synergistic … Read More

Toxicokinetics and Molecular Targets of Herb-Drug Interactions

Runzi Wang

pp.65-70 DOI: 10.62051/83vvpg60

Abstract: This review focus on the impact of Chinese herbal medicine on most of the body systems in animals and humans. There are advantages and drawbacks in Traditional Chinese Medicines (TCMs), since different dosages and types of active ingredients in TCM could cause different extents of side effects and cure certain diseases at the same time. Common side-effects include liver and kidney damage, allergic reaction, increase the possibility of bleeding, and some might contain heavy metals such as lead … Read More

Identification of Concentration Drivers for Male Fetal Free DNA Based on Multiple Linear Regression and Correlation Analysis

Xiaoxin Lin, Xiaoting Liao, Yilin Cai, Huixian Lin

pp.71-81 DOI: 10.62051/v47rgf44

Abstract: Addressing the challenge that Y-chromosome concentration in male fetuses during non-invasive prenatal testing is influenced by multiple maternal physiological and technical factors, this study utilized data from 1,082 clinical samples to construct a data-driven model for identifying and quantifying concentration drivers. The study first converted text-based gestational age uniformly into days using a gestational age conversion function. Categorical variables such as mode of delivery and parity … Read More

The 6-OHDA Model of Parkinson’s Disease: Mechanisms, Applications, and Limitations

Yiyi Ma

pp.82-88 DOI: 10.62051/2v1mqa20

Abstract: Parkinson's disease (PD) is the second most prevalent progressive neurodegenerative disorder, in which the dopaminergic neurons are lost. Genetic and environmental factors are involved in the onset of PD. Symptoms such as tremor, balance problems, nerve pain, muscle stiffness, and mental issues are the most common. Despite the progress made in the understanding of the features of PD, the precise mechanisms responsible for the neuronal degeneration are not well understood. Consequently, animal … Read More

Daraxonrasib Treatment in RAS-Mutated Pancreatic Cancer: Mechanisms, Clinical Evidence and Future Perspectives

Zhouyu Song

pp.89-96 DOI: 10.62051/ndcdrx21

Abstract: Pancreatic ductal adenocarcinoma (PDAC) ranks among the deadliest malignancies worldwide, with its poor prognosis stemming from aggressive progression, delayed detection, and limited treatment responses. While KRAS has attracted substantial interest as a therapeutic target, its molecular architecture long defied direct pharmacological intervention. The recent introduction of daraxonrasib (RMC-6236)—a multiselective RAS(ON) inhibitor capable of engaging multiple active RAS variants—marks a … Read More

Principles and Development of Drinking Water Purification Technology

Zihan Zhou

pp.97-104 DOI: 10.62051/ssv6zn58

Abstract: The presented paper studies the purification process of water used for drinking, its ways and principles, and its historical evolution. Impure water can be a cause of many dangerous diseases that can take lives. According to the WHO report, 1.4 million people die every year due to polluted water. This paper explores the historical background of water purification, its recent methods, and its aftereffects. In the past, it started from ancient Egypt’s alum (saltish mineral) and Greek cloth filters … Read More

Comparative Analysis of Chinese and American Dietary Guidelines

Meixuan Ji

pp.105-110 DOI: 10.62051/6rn9ns03

Abstract: Dietary guidelines are authoritative reference documents developed based on the national health status, nutritional science research, and dietary cultures of various countries, playing a pivotal role in guiding residents toward balanced diets, preventing chronic diseases, and enhancing public health literacy. This paper conducts a comprehensive comparison between the *China Dietary Guidelines for the Population (2022) * and the *Dietary Guidelines for Americans (2025-2030) * across five … Read More

Artificial Intelligence-Based Prediction of Marine Microbial Biogeochemical Activity Using Multi-Omics Data

Yue Li

pp.111-120 DOI: 10.62051/5nfey553

Abstract: Marine microorganisms play a crucial role in global biogeochemical cycles, and accurately predicting their biogeochemical activities is essential for understanding changes in marine ecosystems. Addressing the challenges of high dimensionality, strong heterogeneity, and complex nonlinear relationships in multi-omics data, this paper proposes a deep learning prediction framework based on multi-omics fusion: AE-GAT-AFNet. This method first utilizes an autoencoder (AE) to perform feature compression … Read More

Research on Tomato Quality Prediction and Fish Disease Diagnosis Based on Multimodal Data

Zihang Gao, Xiaojun Cui

pp.121-125 DOI: 10.62051/mcwkzq47

Abstract: We propose a multimodal data-driven scheme for intelligent tomato quality prediction and fish disease diagnosis to advance smart protected agriculture and modern aquaculture. Integrating multi-source environmental, visual and managerial data, we construct a full-cycle tomato dataset and develop AI prediction and decision models to address the insufficient digitization and experience-dependent management in traditional tomato cultivation. Targeting aquaculture complexity, this work builds a … Read More