Graphene-Based Nanomaterial and Its Applications as Drug Nanocarrier

Yucong Sun

pp.1-5 DOI: 10.62051/qdeehv75

Abstract: Graphene-based nanomaterial can be used in many fields due to its excellent properties. Nowadays, it is widely used in drug delivery systems as nanocarriers due to its unique structure, large surface area, and biocompatibility. It can be more easily combined with other nanoparticles through modification. Cancer is a disease with a high mortality rate. It remains the top rank leading to death for many years. In order to treat cancer, using graphene and its derivatives as nanocarriers to transport … Read More

Progress in the Synthesis and Application of Biodegradable Polymers

Yulin Sun

pp.6-12 DOI: 10.62051/209rhe78

Abstract: With the development of science and technology, biodegradable materials have gradually emerged in people's vision. Biodegradable materials are generally high polymer materials, many of which can be artificially synthesized, and some raw materials are simple and easy to obtain, and the production process is not complicated. This material has many advantages that traditional materials cannot match, and it can be said that the current development prospects of this material are very promising. Its … Read More

Enzyme Immobilization Based on Metal-Organic Frameworks and Its Biosensing Applications

Feilu Sun

pp.13-19 DOI: 10.62051/rbkrjx23

Abstract: Many studies have shown that metal-organic frameworks (MOFs) that immobilized enzymes have broad application prospects. As highly efficient biological catalase, enzymes are easily inactivated under some special conditions, which becomes a major obstacle to industrial catalysis and hinders their wide application. However, when the enzyme is immobilized, its disadvantages such as instability and low recyclability are improved, resulting in higher catalytic efficiency and cost savings. The use of … Read More

Application of Flexible Wearable Sensors for Revolution of Personalized Medicine in the Age of Digital Health

Wenfei Yu

pp.20-24 DOI: 10.62051/nzhrvy28

Abstract: With the advent of the digital health era, flexible wearable sensors show great potential in personalized medicine and health monitoring. This research discusses recent advances in polymer-based flexible sensors that enable real-time, non-invasive monitoring of vital signs and physiological parameters, which are essential for early diagnosis and timely intervention in health conditions. Researchers are developing new flexible materials to adapt to the shape and dynamics of the human body while … Read More

Optimization of Electrochemical Sensors and Their Application in CO2 Detection

Hongyi Zhang

pp.25-30 DOI: 10.62051/m8ww7q92

Abstract: In response to the increasing global greenhouse gas content, electrochemical sensors with the advantages of existing main detection methods have the problem of being very sensitive to temperature, and long-term exposure to greenhouse gases will seriously affect the service life. From the aspects of sensitivity, selectivity, internal structure and working principle, this research points out the research progress of existing electrochemical sensors for detecting carbon dioxide (CO2), which consist … Read More

Gold Nanoparticles (Aunps)-Based Biosensors for Cancer Detection

Chuxian Gao, Zhizhou Jiang

pp.31-35 DOI: 10.62051/r1stwf61

Abstract: Gold nanomaterials have shown unique advantages in constructing biosensors due to their special optical and electrochemical properties, and have been widely used. This paper investigates improved gold nanoparticles (AuNPs) applications in biosensors for early cancer detection, focusing on the use of AuNPs to improve diagnostic sensitivity and specificity. The introduction emphasizes the critical need for precise early detection technology that can improve cancer treatment outcomes. It describes … Read More

Analysis of Non-Invasive Diabetes Detection Technology

Ayimureke Asikar

pp.36-42 DOI: 10.62051/kv42pk68

Abstract: Diabetes mellitus is a chronic disease caused by a combination of genetic, environmental, and lifestyle factors, posing a serious threat to public health worldwide. Traditional blood glucose monitoring methods have the disadvantages of high invasiveness, complicated operation, and poor portability, which affect the testing experience of patients and the effectiveness of disease management. Therefore, the search for new non-invasive, convenient and accurate diabetes detection methods has become a … Read More

Metal-Organic Frameworks-Based Electrocatalytic Reduction of CO2

Chao Zhang

pp.43-50 DOI: 10.62051/8w4yjg12

Abstract: Given the increasing emphasis on carbon dioxide (CO2), diverse approaches have been developed and then used to address the issue. Metal-organic frameworks (MOFs) have shown promise in catalyzing the electrochemical reduction of CO2. Different types of MOFs have investigated, including Cu-MOFs, Ce-MOFs, and hybrid composites, in order to enhance the catalytic selectivity, activity, and stability of electrocatalysts. MOFs possess distinct structural characteristics such as a large surface area, … Read More

Nanomaterials-Based Electrochemical Sensors for Heavy Metal Ions Detection

Ziqian Zhao

pp.51-55 DOI: 10.62051/dryvdg59

Abstract: The emission and accumulation of heavy metals have been damaging our living situation. The ultrasensitive detection for heavy metal ions is an important area as it can alarm for pollution to protect the environment and help individual health. Electrochemical sensors known as the potential detecting methods attract the researcher’s attention and combined with nanomaterial constitute an active research area that could give opportunities for further development in heavy metal detection performance. … Read More

Detection of Nanoplastics Within Complex Environmental and Food Resources Matrices Via Machine Learning

Henry Jin

pp.56-68 DOI: 10.62051/78e2m545

Abstract: The pervasiveness of nanoplastics within the environment underscores the need for robust and accurate methods for their identification and classification. The lightweight and small nanoplastics (NPs) can bypass biological barriers and disperse throughout the environment, posing significant health risks to humans and aquatic life. Typical detection of nanoplastics has relied on cumbersome filtration, and subsequent coloration of the plastics for visualization, once they have been painstakingly … Read More

Application of Nanoparticles in Cosmetics

Guanxi Meng

pp.69-75 DOI: 10.62051/qcyb3q83

Abstract: The application of nanotechnology in cosmetics can explore the greatest potentials of active substances, leading to improved performance of cosmetics. However, the safety of nanoparticles is still controversial. This review aims to summarize the application and impact of nanotechnology in cosmetics. The advantages and potential drawbacks of nanoparticles in augmenting cosmetic absorption were discussed. A meticulous analysis is conducted to explore how nanomaterials are ingeniously utilized … Read More

Recent Application of Nanopores in the Detection of Small Organic Molecules

Yunxi Zhong

pp.76-81 DOI: 10.62051/qmxc3d44

Abstract: Nanopore sensors have become a useful tool for detecting small organic molecules, which provides more and more accurate options than traditional analytical techniques. This review outlines and compare the application of various emerging nanopore sensors, which includes solid-state nanopore (silicon nitride and MsO2) and non-solid-state nanopore (α-hemolysin nanopore, aerolysin nanopore, MspA and so on), to identify various organic molecules, including amino acids, nucleotides monosaccharides and … Read More

The Analysis of Toxicity and Safety of Nano Particles Applied in Sunscreen

Daolin Zuo

pp.82-87 DOI: 10.62051/pzb7aa82

Abstract: Nano particles (NPs) with size from 1 to 100nm had been developed fast from 1950s. They are highly stable, hydrophilic and biocompatible. These NPs possess transparency and UV-absorbing properties, making them effective as protective filters. Different kinds of NPs had been applied in sunscreen. However, due to the size of metal NPs, they can easily pass-through human skin. After that, these NPs could enter the organs and the circulation system in human body. For the biochemical reactions with … Read More

Recent Advances of Drug Design Strategies for Classical KRAS Mutations

Xulin Huang

pp.88-93 DOI: 10.62051/yc6p5d86

Abstract: KRAS, one of the most common oncogenic mutations, is considered to be a potential target for design of cancer therapies. Previous studies have suggested a poor therapeutic index and lack of efficacy of drugs targeting the KRAS signalling pathway and even leading to think “undrugged”. But recently, major breakthrough in KRAS was achieved in a decade and even up to hit the market which really inspired a lot. This review aims to illustrate the recent advances of drug design strategies for different … Read More

A New Frontier in Ferroptosis-Driven Cancer Treatment

Tzu-Hsuan Shang, Cheng Zheng

pp.94-101 DOI: 10.62051/t738nn19

Abstract: Ferro ptosis, as an iron-dependent form of regulated cell death fundamentally controlled by lipid peroxidation, has been discovered to be effective in cancer therapy. However, in contrast to traditional treatment methods such as chemotherapy and radiation, ferroptosis specifically targets and destroys cancerous cells. Nevertheless, ferroptosis faces significant obstacles, including low tumour penetration, off-target toxicity, and poor solubility. Nanotechnology, namely the design of … Read More

Recent Advances in Nano Silver Catalysis for Organic Transformations

Yuxuan Du

pp.102-108 DOI: 10.62051/kzr77t36

Abstract: This account explains three types of reactions to form homogeneous or heterogeneous nanocatalysts; coupling reaction, reduction reaction, and cascade reaction. Catalyst is an important technology and has various advantages. Metal oxides, or metals, placed on a support or carrier in a different state, are the catalytically active part of a solid catalyst. Particles that range in size from 1 to 100 nm are referred to as metal nanoparticles, and they are frequently used in synthetic organic … Read More

Recent Advances of Nanozymes as Therapies for ROS-Induced Diseases

Jiabao Shi

pp.109-117 DOI: 10.62051/8xzp5k10

Abstract: Recently nanozymes have received more and more attention and have been applied in many fields. Recent advances of applications of nanozymes as therapies for various reactive oxygen species (ROS)-induced diseases are summarized in this account. For each case, the rational design strategies as well as various factors regulating the multiple enzyme-like activities, are also discussed. Perspectives and Challenges are also mentioned. Read More

Application of Different Biosensors for Cancer Detection

Xueyan Chen

pp.118-124 DOI: 10.62051/mqpms008

Abstract: Cancer is one of the main causes of death for humans while early detection can greatly lower cancer mortality and save lives. Therefore, reliable, cost-effective, and powerful technologies to detect the disease are needed. Cancer biomarkers are substances such as nucleic acids, enzymes, and metabolites, present in cancer clusters, tumours, or serum. While biosensors provide a quick, accurate, sensitive, uncomplicated, and economical method of diagnosing a particular cancer biomarker and is … Read More

Application of Continuous Glucose Monitoring for Diabetes Detection

Mingxi Pan

pp.125-129 DOI: 10.62051/wpmypn26

Abstract: Diabetes is a serious chronic disease characterized by high blood glucose. The prevalence of diabetes is very high in the whole world. If isn’t monitored and unmanaged, diabetes can lead to many severe health complications such as heart disease, stroke and kidney disease. Implantable continuous glucose monitoring (CGM) system is the current technique for monitoring the concentration of blood glucose for diabetes patients. There were two common types of implantable CGM in the market, which were … Read More

Revolutionizing Cancer Genomics: AI-Driven Interpretation of Nanopore Sequencing Signals

Dan Sun

pp.130-135 DOI: 10.62051/g8rwwe94

Abstract: Nanopore sequencing technology enables the detailed analysis of biomolecules such as DNA and RNA by detecting variations in ionic current as these molecules traverse nano-scale pores. This method captures nuanced patterns, including sequence context and modification signatures. This research investigates the application of artificial intelligence (AI), particularly deep learning models such as SquiggleNet, NanoDeep, and DeepMod2, in analyzing nanopore sequencing data. The performance metrics of … Read More

Gold Nanomaterials in Biosensing Applications

Xinlin Zuo

pp.136-143 DOI: 10.62051/cvrcdm56

Abstract: This paper provides an overview of the preparation and application of gold nanomaterials in biosensing, including four aspects: biomolecular detection, medical bioimaging, pathogen detection, and immunoassay. Firstly, the preparation methods of gold nanomaterials are introduced, including chemical reduction, laser radiation, and vacuum evaporation. Secondly, the applications of gold nanomaterials biosensors in various fields are outlined. One such field is biomolecule detection. gold … Read More

Research Progress on Synthesis of Nano Strontium Titanate for Photocatalytic Applications

Ke-chieh Chen

pp.144-150 DOI: 10.62051/nrb7zw72

Abstract: Environmental pollution and energy shortages pose a significant threat to human life and development in today's industry. Therefore, this essay aims to review the various methods used in the synthesis of nano strontium titanate photocatalysis. These synthesis methods can be tailored to meet different research needs and control the morphology, size, and properties of materials under varying conditions. The methods of synthesis include the solid-phase method, hydrothermal synthesis method, sol-gel … Read More

The Progress of Cathode and Electrolyte for Low Temperature Sodium-Ion Battery

Jingtong Zhou

pp.151-157 DOI: 10.62051/hj2z2c69

Abstract: The expanding demand for efficient energy storage systems that operate effectively in low-temperature environments has led to increased research interest in sodium-ion batteries (SIBs) due to their affordability, safety, and the abundance of sodium resources. With the development of industry, SIBs need to face the challenge of extreme temperatures, especially at low temperatures where the decrease in ion conductivity leads to a significant decrease in SIB capacity. This review article presents a … Read More

Advancements in Low-Temperature Lithium Metal Batteries: A Comprehensive Review

Aoxuan Li

pp.158-166 DOI: 10.62051/7p9bam47

Abstract: Lithium metal batteries (LMB) represent a major advance in energy storage technology, offering a huge high energy density, and have the potential to be used in important fields such as electric vehicles and aerospace. However, their practical application at low temperatures still faces major challenges. This paper reviews recent advances in overcoming these obstacles, including the development of ether-based and fluorated electrolytes to reduce dendrite formation, improve SEI stability, and the … Read More

Pharmacokinetics and Pharmacological/Bioactive Studies of Oridonin Derivatives in Anti-tumor Research

Yao Sang

pp.167-177 DOI: 10.62051/cne0eh26

Abstract: Objective: it to investigate the pharmacokinetics of oridonin derivatives and their effects on tumor cell proliferation (Pro), invasion (Inv), and apoptosis (Apo), aiming to provide a theoretical basis for cancer treatment. Materials and Methods: drug and statistics (DAS) software was utilized to analyze the average blood concentration-time data collected, determining pharmacokinetic parameters. Human breast cancer MCF-7 cells were used as experimental cells. Cells were rolled into three groups: … Read More

Research on the Model of Interlayer Melt Blown Non-woven Materials Based on Regression Prediction

Qianting Deng, Sitong Peng, Guanting Wu, Zhifeng Lin

pp.178-185 DOI: 10.62051/vpkbjg48

Abstract: Melt blown nonwoven materials are currently widely used air filtration materials, with fine fibers, large specific surface area, good fluffiness, multiple pores, and excellent filtration performance. After polar treatment, filtration efficiency can be greatly improved without increasing filtration resistance. Melt blown nonwoven materials are important raw materials for mask production, and their various excellent characteristics have attracted widespread attention from domestic and foreign … Read More

This paper analyzes and identifies the composition of ancient glass products by using data analysis method

Runhe Tang, Jingyi Zhou

pp.186-197 DOI: 10.62051/yd5gqx83

Abstract: Glass is the precious material evidence of the ancient Silk Road trade. China's ancient glass and foreign glass, although similar in appearance, but the chemical composition is different. Ancient glass is susceptible to environmental influences and thus weathering, and the weathering process will affect the change of its chemical composition, so it is necessary to study the relationship between weathering and some characteristics of glass. First of all, this paper uses the method of Chi-square … Read More

Process Design of CDMO Aseptic Formulation Workshop for PD-1 Antibody and Protein Products

Jinjie Zhu, Songzhi Li, Siwen Wang, Chengyu Chen, Xiaochao Zhen

pp.198-212 DOI: 10.62051/gewhn079

Abstract: With the rapid development of biotechnology and the improvement of global health awareness, the biopharmaceutical industry has developed rapidly. The CDMO model has become an important means for many biopharmaceutical enterprises to optimize resource allocation and improve research and development efficiency. The aim of this study is to provide a scientific and cost-effective sterile formulation workshop design scheme that meets GMP requirements. The study aims to avoid potential risks to … Read More

Study on Ancient Glass Classification Based on Fisher Linear Discriminant Analysis and Systematic Cluster Analysis

Yifan Fu, Yudi Lin, Jian Chen, Jiaxin Chen, Zhenni Chen

pp.213-221 DOI: 10.62051/r2171v16

Abstract: This paper discusses the classification of high potassium glass and lead-barium glass, and puts forward the model establishment and solution method using Fisher linear discriminant analysis and system cluster analysis. This PAPER points out THE obvious changes of chemical composition in glass cultural relics, and explores the classification rules of glass according to the different weathered states. The establishment of the model includes the steps of index selection, training group and test … Read More

Analyzing Lamprey Population Growth and Sex Ratio Evolution Through Cellular Automata and Impact of Predation Efficiency and Sex Ratio on Lamprey Populations

Liwen He, Zilin Cong, Yanjing Cai

pp.222-230 DOI: 10.62051/4wbwpw76

Abstract: Lamprey plays an important role in the ecosystem, and studying its population dynamics and the evolution of sex ratio is essential to maintaining the balance of the ecosystem. Faced with the challenges of complex environmental interactions and changes in population parameters, this study simulates the impact of gender ratio shifts on lamprey populations, revealing that imbalanced sex ratios can reduce growth and alter community dynamics. Adult mortality and recruitment rates significantly affect … Read More

The Application of Pd-Based Nanomaterials for Methanol Oxidation and Oxygen Reduction Reaction in The Direct Methanol Fuel Cells

Runhan Zhai

pp.231-241 DOI: 10.62051/2jynp742

Abstract: Direct methanol fuel cells (DMFC) are considered as a sustainable and environment-benign energy source which provide electrical energy from chemical energy with less pollution, higher efficiency, and noiseless operation. In this review, the application of the Pd-based nanomaterials for the oxygen reduction reaction(ORR) that is carried out on the cathode and the methanol oxidation reaction(MOR)that is carried out on the anode are discussed in the direct methanol fuel cells. At first, the … Read More

The Permian-Triassic Extinction Event: Causes, Consequences, and Contemporary Relevance

Sirui Shen

pp.242-248 DOI: 10.62051/gs9fsn90

Abstract: This study presents an overview of the Permian-Triassic extinction event — recognized as the most catastrophic biotic crisis that has occurred on Earth. We trace the path of scientific discovery with respect to the timing, scale, and causation of this dual-phased calamity. A comparison is made between its effects on marine and terrestrial ecosystems; note that 96% of all marine species and later 70% of all terrestrial vertebrate species were wiped out during these extinctions. Consider now the … Read More

Gene Therapy for Treating Diabetes

Yuelin Jing

pp.249-255 DOI: 10.62051/9k24rk13

Abstract: Diabetes has already been a worldwide issue.it is a type of chronic disease with a high risk and a high number of cases. The main symptom of diabetes is not only the spike in blood sugar after eating and the difficulty in lowering it, but the numerous complications are also noteworthy. Currently, traditional treatments for diabetes include controlling sugar intake in the diet and insulin injection therapy. However, traditional diabetes treatments are not ideal. This is mainly due to the fact … Read More